| نویسندگان | Saeedi M., Khoshdoun M., Taheri S., Ziyaei Halimehjani A., Mohammadi A., Halvagar M.R., Amani V. |
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| نشریه | SynOpen |
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| كد DOI/DOR | 10.1055/a-1492-9229 |
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| تاریخ انتشار | ۲۰۲۱ |
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چکیده مقاله
An efficient method for the synthesis of highly substituted bicyclic pyridone derivatives containing the dithiocarbamate group is reported via a one-pot three-component reaction of 2-(alkylthio)thioazlactones, diamines, and nitroketene dithioacetal in EtOH under catalyst-free conditions. The reaction proceeds via a domino amidation-intramolecular 1,4-addition-type Friedel-Crafts alkylation reaction to afford the corresponding fused bicyclic pyridones with high yields and diastereoselectivity. © 2021. The Author(s).
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