The reaction of N-isocyaniminotriphenylphosphorane with cyclopentanone and a primary amine in the presence of an E-cinnamic acid derivative

چکیده مقاله

Reactions of N-isocyaniminotriphenylphosphorane with cyclopentanone in the presence of an E-cinnamic acid derivative and a primary amine proceeds smoothly at room temperature and in neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives in high yields. The reaction proceeds smoothly and cleanly under mild conditions and no side reactions were observed. © 2014 Taylor & Francis Group, LLC.